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Literature summary for 3.4.17.22 extracted from

  • Maenz, C.; Chang, S.F.; Iwanski, A.; Bruns, M.
    Entry of duck hepatitis B virus into primary duck liver and kidney cells after discovery of a fusogenic region within the large surface protein (2007), J. Virol., 81, 5014-5023.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine for infection of primary duck hepatocytes with duck hepatitis B virus, binding of the pre-S domain of the large surface protein to the cellular glycoprotein gp180 as a ubiquitous carboxypeptidase is required Anas platyrhynchos

Protein Variants

Protein Variants Comment Organism
additional information a noninfectious pre-S deletion mutant devoid of the binding region for carboxypeptidase D can be rendered infectious for primary duck hepatocytes by treatment with chymotrypsin Anas platyrhynchos

Organism

Organism UniProt Comment Textmining
Anas platyrhynchos
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
hepatocyte
-
Anas platyrhynchos
-
liver
-
Anas platyrhynchos
-

Synonyms

Synonyms Comment Organism
Carboxypeptidase D
-
Anas platyrhynchos
gp180
-
Anas platyrhynchos