Literature summary for 3.4.17.21 extracted from

Hicks, C.; Gregg, R.A.; Nayak, S.U.; Cannella, L.A.; Schena, G.J.; Tallarida, C.S.; Reitz, A.B.; Smith, G.R.; Rawls, S.M.
Glutamate carboxypeptidase II (GCPII) inhibitor 2-PMPA reduces rewarding effects of the synthetic cathinone MDPV in rats a role for N-acetylaspartylglutamate (NAAG) (2017), Psychopharmacology, 234, 1671-1681 .

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Inhibitors

Inhibitors	Comment	Organism	Structure
2-(phosphonomethyl)pentanedioic acid	-	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	P70627	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
prefrontal cortex	withdrawal of 3,4-methylenedioxypyrovalerone reduces expression of glutamate carboxypeptidase II in the prefrontal cortex	Rattus norvegicus	-

Synonyms

Synonyms	Comment	Organism
GCPII	-	Rattus norvegicus
glutamate carboxypeptidase II	-	Rattus norvegicus

Expression

Organism	Comment	Expression
Rattus norvegicus	withdrawal of 3,4-methylenedioxypyrovalerone reduces expression of glutamate carboxypeptidase II in the prefrontal cortex	down

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Release 2023.1 (January 2023)