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Literature summary for 3.4.17.21 extracted from

  • Lopreato, F.R.; Stabler, S.P.; Carvalho, F.R.; Hirata, R.D.; Hirata, M.H.; Robi, D.L.; Sampaio-Neto, L.F.; Allen, R.H.; Guerra-Shinohara, E.M.
    Relationships between gene polymorphisms of folate-related proteins and vitamins and metabolites in pregnant women and neonates (2008), Clin. Chim. Acta, 398, 134-139.
    View publication on PubMed

Application

Application Comment Organism
medicine maternal total homocysteine concentration is affected by C1561T polymorphism, maternal GCPII C1561T variant is associated with neonatal methylmalonic acid concentration Homo sapiens

Protein Variants

Protein Variants Comment Organism
H475Y C1561T single nucleotide polymorphism located in the putative catalytic region of the enzyme Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
brush border intestinal brush border membrane Homo sapiens 5903
-
membrane
-
Homo sapiens 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens intestinal absorption of polyglutamyl folates involves cleavage of the glutamate side chain by FGCP ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information intestinal absorption of polyglutamyl folates involves cleavage of the glutamate side chain by FGCP Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
FGCP
-
Homo sapiens
folylpoly-gamma-glutamate carboxypeptidase II
-
Homo sapiens
GCPII
-
Homo sapiens
glutamate carboxypeptidase II
-
Homo sapiens