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Literature summary for 3.4.17.21 extracted from

  • van der Post, J.P.; de Visser, S.J.; de Kam, M.L.; Woelfler, M.; Hilt, D.C.; Vornov, J.; Burak, E.S.; Bortey, E.; Slusher, B.S.; Limsakun, T.; Cohen, A.F.; van Gerven, J.M.
    The central nervous system effects, pharmacokinetics and safety of the NAALADase-inhibitor GPI 5693 (2005), Br. J. Clin. Pharmacol., 60, 128-136.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
pharmacology the enzyme NAALADase is a target for drug treatment in neuropathic pain Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
GPI 5693 i.e. (R,S)-2-(3-mercaptopropyl)-pentanedioic acid or 2-MPPA, pharmacokinetics and safety of the NAALADase-inhibitor and its effects on the central nervous system after application in vivo, overview Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
central nervous system
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
NAALADase
-
Homo sapiens