Literature summary for 3.4.17.21 extracted from

Nan, F.; Bzdega, T.; Pshenichkin, S.; Wroblewski, J.T.; Wroblewska, B.; Neale, J.H.; Kozikowski, A.P.
Dual function glutamate-related ligands: discovery of a novel, potent inhibitor of glutamate carboxypeptidase II possessing mGluR3 agonist activity (2000), J. Med. Chem., 43, 772-774.

Inhibitors

Inhibitors	Comment	Organism	Structure
5-oxoheptane-1,3,7-tricarboxylic acid	0.1 mM, 35% inhibition	Rattus norvegicus
5-oxononane-1,3,7,9-tetracarboxylic acid	inhibitor possesses mGluR3 agonist activity	Rattus norvegicus

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	stably expressed in CHO cells	-

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)