Literature summary for 3.4.17.21 extracted from

Rojas, C.; Frazier, S.T.; Flanary, J.; Slusher, B.S.
Kinetics and inhibition of glutamate carboxypeptidase II using a microplate assay (2002), Anal. Biochem., 310, 50-54.

Search for more literature for 3.4.17.21

Inhibitors

Inhibitors	Comment	Organism	Structure
2-(phosphonomethyl)pentanedioic acid	competitive	Homo sapiens

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
130	-	N-acetyl-Asp-Glu	pH 7.4, 37°C	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
N-acetyl-Asp-Glu + H2O	-	Homo sapiens	N-acetyl-Asp + Glu	-	?

Synonyms

Synonyms	Comment	Organism
GCPII	-	Homo sapiens
NAALADase	-	Homo sapiens
Prostate-specific membrane antigen	-	Homo sapiens

Turnover Number [1/s]

Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
4	-	N-acetyl-Asp-Glu	pH 7.4, 37°C	Homo sapiens

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.0000002	-	2-(phosphonomethyl)pentanedioic acid	pH 7.4, 37°C	Homo sapiens

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Release 2023.1 (January 2023)