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Literature summary for 3.4.17.20 extracted from

  • Frere, C.; Morange, P.E.; Saut, N.; Tregouet, D.A.; Grosley, M.; Beltran, J.; Juhan-Vague, I.; Alessi, M.C.
    Quantification of thrombin activatable fibrinolysis inhibitor (TAFI) gene polymorphism effects on plasma levels of TAFI measured with assays insensitive to isoform-dependent artefact (2005), Thromb. Haemost., 94, 373-379.
    View publication on PubMed
Search for more literature for 3.4.17.20

Cloned(Commentary)

Cloned (Comment) Organism
TAFI gene genotyping, polymorphisms lead to 25% of TAFI level variety, especially due to polymorphisms at 5'-G1102T and 3'-T1583A, isozyme variations at residue 325 being Thr or Ile, overview Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
 Homo sapiens
-
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 two isozymes T325 and I325
-

Purification (Commentary)

Purification (Comment) Organism
from plasma Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme assay using a specific chromogenic dipeptide substrate Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
TAFI
-
 Homo sapiens
thrombin activatable fibrinolysis inhibitor
-
 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.3 7.6 assay at Homo sapiens