Literature summary for 3.4.17.20 extracted from

Campbell, W.D.; Lazoura, E.; Okada, N.; Okada, H.
Inactivation of C3a and C5a octapeptides by carboxypeptidase R and carboxypeptidase N (2002), Microbiol. Immunol., 46, 131-134.

Search for more literature for 3.4.17.20

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
His-Lys-Asp-Met-Gln-Leu-Gly-Arg + H2O	Homo sapiens	i.e. C5a, the enzyme significantly contributes to the inactivation of C5a, the most potent of the complement derived anaphylatoxins	His-Lys-Asp-Met-Gln-Leu-Gly + Arg	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
Ala-Ser-His-Leu-Gly-Leu-Ala-Arg + H2O	reaction is much more efficient than reaction with EC 3.4.17.3	Homo sapiens	Ala-Ser-His-Leu-Gly-Leu-Ala + Arg	-	?
His-Lys-Asp-Met-Gln-Leu-Gly-Arg + H2O	i.e. C5a, reaction is much more efficient than reaction with EC 3.4.17.3	Homo sapiens	His-Lys-Asp-Met-Gln-Leu-Gly + Arg	-	?
His-Lys-Asp-Met-Gln-Leu-Gly-Arg + H2O	i.e. C5a, the enzyme significantly contributes to the inactivation of C5a, the most potent of the complement derived anaphylatoxins	Homo sapiens	His-Lys-Asp-Met-Gln-Leu-Gly + Arg	-	?

Synonyms

Synonyms	Comment	Organism
TAFI	-	Homo sapiens
thrombin-activatable fibrinolysis inhibitor	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)