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Literature summary for 3.4.17.20 extracted from
- Carboxypeptidase U, a plasma carboxypeptidase with high affinity for plasminogen (1994), J. Biol. Chem., 269, 15937-15944.
General Stability
| General Stability | Organism |
|---|---|
| very unstable in gel filtration procedures | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1,10-phenanthroline | - |
Homo sapiens |  |
| 2-Guanidinoethylmercaptosuccinic acid | i.e. GEMSA | Homo sapiens | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 1.12 | - |
hippuryl-L-Arg | - |
Homo sapiens | |
| 1.45 | - |
Hippuryl-L-Lys | - |
Homo sapiens | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Zn2+ | metalloproteinase | Homo sapiens | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 53000 | - |
x * 53000, SDS-PAGE, gel filtration after treatment with guanidine-HCL | Homo sapiens |
| 435000 | - |
gel permeation chromatography | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| plasma | - |
Homo sapiens | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 2000 | - |
- |
Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Hippuryl-L-Arg + H2O | - |
Homo sapiens | Hippuric acid + L-Arg | - |
? | |
| Hippuryl-L-argininic acid + H2O | - |
Homo sapiens | Hippuric acid + argininic acid | - |
? | |
| Hippuryl-L-Lys + H2O | - |
Homo sapiens | Hippuric acid + L-Lys | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 53000, SDS-PAGE, gel filtration after treatment with guanidine-HCL | Homo sapiens |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 4 | - |
at 4°C higher stability than at 30°C, but nevertheless unstable | Homo sapiens |
| 30 | - |
half-life 60 min | Homo sapiens |
| 37 | - |
30 min, 80% loss of activity | Homo sapiens |
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Release 2023.1 (January 2023)
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