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Literature summary for 3.4.17.2 extracted from

  • Lepus, C.; Song, J.; Wang, Q.; Wagner, C.; Lindstrom, T.; Chu, C.; Sokolove, J.; Leung, L.; Robinson, W.
    Carboxypeptidase B serves as a protective mediator in osteoarthritis (2014), Arthritis Rheum., 66, 101-106.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.17.2

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Mus musculus
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-
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Source Tissue

Source Tissue Comment Organism Textmining
synovial tissue in synovial fluids from osteoarthritis patients, high levels of proCPB are associated with high levels of proinflammatory cytokines and complement components, and levels of proCPB correlated positively with those of membrane attack complex (MAC) Homo sapiens
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Synonyms

Synonyms Comment Organism
carboxypeptidase B
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 Mus musculus
carboxypeptidase B
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 Homo sapiens
CPB
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 Mus musculus
CPB
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 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens in synovial fluids from osteoarthritis patients CPB expression is up-regulated up

General Information

General Information Comment Organism
malfunction Cpb2 knockout mice develop greater cartilage damage than wild-type mice and have a greater number of osteophytes and degree of synovitis Mus musculus
malfunction Cpb2 knockout mice develop greater cartilage damage than wild-type mice and have a greater number of osteophytes and degree of synovitis Homo sapiens