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Literature summary for 3.4.17.12 extracted from
- Degradation of bradykinin, a cardioprotective substance, during a single passage through isolated rat-heart (2006), Arch. Pharm. Res., 29, 241-248.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg + H2O | Rattus norvegicus | bradykinin | Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe + arginine | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
male Sprague Dawley rat | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| endothelium | arterial endothelium | Rattus norvegicus | - |
| heart | coronary vascular bed | Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg + H2O | bradykinin | Rattus norvegicus | Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe + arginine | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| carboxypeptidase M | - |
Rattus norvegicus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
hearts are perfused with Krebs Henseleit solution at a rate of 10 ml per min, perfusate samples are analysed and bradykinin metabolites are characterized | Rattus norvegicus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.4 | - |
hearts are perfused with Krebs Henseleit solution at a rate of 10 ml per min, perfusate samples are analysed and bradykinin metabolites are characterized | Rattus norvegicus |
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Release 2023.1 (January 2023)
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