Literature summary for 3.4.17.10 extracted from

Xiao, L.; Yang, X.; Sharma, V.K.; Loh, Y.P.
Cloning, gene regulation, and neuronal proliferation functions of novel N-terminal-truncated carboxypeptidase E/neurotrophic factor-alphaIl variants in embryonic mouse brain (2019), FASEB J., 33, 808-820 .

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Cloned(Commentary)

Cloned (Comment)	Organism
N-terminal-truncated carboxypeptidase E/neurotrophic factor-alpha1 variants in embryonic mouse brain. It has an important, enzymatically independent role in the regulation of genes critical for neurodevelopment	Mus musculus

Protein Variants

Protein Variants	Comment	Organism
additional information	an N-terminal-truncated CPE/NF-alpha1 variant, a 40-kDa protein, is exclusively expressed in embryonic neurons	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	Q00493	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	embryonic	Mus musculus	-
neuron	an N-terminal-truncated CPE/NF-alpha1 variant, a 40-kDa protein, is exclusively expressed in embryonic neurons	Mus musculus	-

Synonyms

Synonyms	Comment	Organism
CPE	-	Mus musculus

General Information

General Information	Comment	Organism
physiological function	the enzyme is involved in proneuropeptide processing. It is also a neurotrophic factor (NF-a1) and has important roles in neuroprotection, stem cell differentiation, and neurite outgrowth, independent of enzymatic activity	Mus musculus

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Release 2023.1 (January 2023)