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Literature summary for 3.4.17.10 extracted from
- Carboxypeptidase E cytoplasmic tail mediates localization of synaptic vesicles to the pre-active zone in hypothalamic presynaptic terminals (2010), J. Neurochem., 114, 886-896.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | Q00493 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| neuron | - |
Mus musculus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| carboxypeptidase E | - |
Mus musculus |
| CPE | - |
Mus musculus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | glutamatergic and acetylcholine synaptic vesicles in the hypothalamus and chromaffin cell-derived PC12 cells employ the transmembrane carboxypeptidase E cytoplasmic tail to interact with gamma-adducin for recruiting synaptic vesicles to the active and/or pre-active zone to facilitate neurotransmitter release. Carboxypeptidase E is a mediator in the process, that mediates localization of synaptic vesicles to the pre-active zone. Carboxypeptidase E has a non-enzymatic role in the control of classical neurotransmitter release in specific neuron | Mus musculus |
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Release 2023.1 (January 2023)
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