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Literature summary for 3.4.17.10 extracted from

  • Park, J.J.; Cawley, N.X.; Loh, Y.P.
    A bi-directional carboxypeptidase E-driven transport mechanism controls BDNF vesicle homeostasis in hippocampal neurons (2008), Mol. Cell. Neurosci., 39, 63-73.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
CPE tail fragments are subcloned into pGEX4T-2, pEGFP-C1 and pDsRed2, full-length CPE cDNA is inserted into pDsRed-Express-N1 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
transport vesicle associated with brain-derived neurotrophic factor, BDNF, vesicles Rattus norvegicus 30133
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus release of C-terminal arginine or lysine residues from polypeptides ?
-
?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
E-18 rat primary hippocampal neuron
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Rattus norvegicus
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neuron hippocampal and cortical neuron Rattus norvegicus
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PC-12 cell
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Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information release of C-terminal arginine or lysine residues from polypeptides Rattus norvegicus ?
-
?

Synonyms

Synonyms Comment Organism
carboxypeptidase E
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Rattus norvegicus
CPE
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Rattus norvegicus