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Literature summary for 3.4.17.10 extracted from

  • Dhanvantari, S.; Arnaoutova, I.; Snell, C.R.; Steinbach, P.J.; Hammond, K.; Caputo, G.A.; London, E.; Loh, Y.P.
    Carboxypeptidase E, a prohormone sorting receptor, is anchored to secretory granules via a C-terminal transmembrane insertion (2002), Biochemistry, 41, 52-60.
    View publication on PubMed
Search for more literature for 3.4.17.10

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane anchored to secretory granules via a C-terminal transmembrane insertion. The membrane-binding domain of the enzyme must adopt an alpha-helical configuration to bind to lipids and the enzyme may require another integral membrane chaperone protein to insert through the lipid bilayer in a transmembrane fashion Bos taurus 16020
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secretory granule from neural lobe pituitary and intermediate lobe pituitary Bos taurus 30141
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Bos taurus the enzyme is a sorting receptor that directs the prohormone pro-opiomelanocortin to the regulated secretory pathway and is also a prohormone processing enzyme in neuro/endocrine cells ?
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
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-
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Source Tissue

Source Tissue Comment Organism Textmining
pituitary gland neural lobe and intermediate lobe pituitary Bos taurus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme is a sorting receptor that directs the prohormone pro-opiomelanocortin to the regulated secretory pathway and is also a prohormone processing enzyme in neuro/endocrine cells Bos taurus ?
-
 ?

Synonyms

Synonyms Comment Organism
CPE
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 Bos taurus