Literature summary for 3.4.17.1 extracted from

VenkatRao, V.; Kumar, S.K.; Sridevi, P.; Muley, V.Y.; Chaitanya, R.K.
Cloning, characterization and transmission blocking potential of midgut carboxypeptidase A in Anopheles stephensi (2017), Acta Trop., 168, 21-28 .

Search for more literature for 3.4.17.1

Application

Application	Comment	Organism
medicine	addition of CPA-directed antibodies to Plasmodium berghei-containing blood meal significantly reduces the mosquito infection rate in the test group compared to control and blocks the parasite development in the midgut	Anopheles stephensi

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Zinc	-	Anopheles stephensi

Organism

Organism	UniProt	Comment	Textmining
Anopheles stephensi	A0A0S2A471	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
midgut	predominantly expressed in the midgut throughout the mosquito life cycle	Anopheles stephensi	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
hippuryl-L-Phe + H2O	-	Anopheles stephensi	hippuric acid + L-Phe	-	?

Subunits

Subunits	Comment	Organism
?	x * 48000, zymogen form, x * 37000, mature form, SDS-PAGE	Anopheles stephensi

Expression

Organism	Comment	Expression
Anopheles stephensi	gene expression is significantly elevated in Plasmodium berghei-infected mosquitoes compared to uninfected blood-fed controls	up

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Release 2023.1 (January 2023)