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Literature summary for 3.4.17.1 extracted from

  • Matsugi, S.; Hamada, T.; Shioi, N.; Tanaka, T.; Kumada, T.; Satomura, S.
    Serum carboxypeptidase A activity as a biomarker for early-stage pancreatic carcinoma (2007), Clin. Chim. Acta, 378, 147-153.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
Trypsin procarboxypeptidase A, pro CPA, is converted into the active form of CPA by trypsin Homo sapiens

Application

Application Comment Organism
medicine assay of total-carboxypeptidase A, the active form of CPA and pro CPA, in serum might be useful for the surveillance of early-stage pancreatic carcinoma Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
DL-benzylsuccinic acid
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
serum
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-acetyl-phenylalanyl-L-3-thiaphenylalanine + H2O assay substrate Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
carboxypeptidase a
-
Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
activity assay Homo sapiens

pH Range

pH Minimum pH Maximum Comment Organism
4 4.9
-
Homo sapiens