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Literature summary for 3.4.16.5 extracted from

  • Kollmann, K.; Damme, M.; Deuschl, F.; Kahle, J.; DHooge, R.; Luellmann-Rauch, R.; Luebke, T.
    Molecular characterization and gene disruption of mouse lysosomal putative serine carboxypeptidase 1 (2009), FEBS J., 276, 1356-1369.
    View publication on PubMed
Search for more literature for 3.4.16.5

Cloned(Commentary)

Cloned (Comment) Organism
expressed in HT-1080 cells Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
lysosome
-
 Mus musculus 5764
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
55000
-
 SDS-PAGE Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus Q920A5
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Mus musculus
-
liver
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information no proteolytic activity or increased serine carboxypeptidase activity towards artificial serine carboxypeptidase substrates of the purified recombinant 55 kDa precursor and the homogenates of Scpep1-overexpressing cells is detected Mus musculus ?
-
 ?

Subunits

Subunits Comment Organism
More consisting of a 35 kDa N-terminal fragment and a 18 kDa C-terminal fragment, the two-chain form of Scpep1 does not form disulfide bridges Mus musculus

Synonyms

Synonyms Comment Organism
Scpep1 formerly retinoid-inducible serine carboxypeptidase Mus musculus
serine carboxypeptidase 1
-
 Mus musculus

General Information

General Information Comment Organism
physiological function Scpep1-deficient mice are viable and fertile, and do not exhibit either lysosomal storage or reduced lysosomal serine carboxypeptidase activity Mus musculus