Activating Compound | Comment | Organism | Structure |
---|---|---|---|
3-Phenyl-1-propanol | inhibits hydrolysis of benzyloxycarbonyl-Phe-Leu, activates hydrolysis of benzyloxycarbonyl-Gly-Phe | Saccharomyces cerevisiae | |
CH3-CH2-CH2-CH2-Hg | mercurials inhibit the hydrolysis of the good substrate benzyloxycarbonyl-L-Phe-L-Leu, the inhibition is repressed by the competitive inhibitors benzyloxycarbonyl-D-Phe-D-Leu-Leu-Phe, trans-cinnamate and acetyl-D-Phe ethyl ester. Aromatic, methyl and ethyl mercurials do not cause complete inactivation with the poor substrates benzyloxycarbonyl-Gly-Phe and benzoyl-Gly-beta,L-phenyllactate. Propyl and butyl-mercurials enhance these activities | Saccharomyces cerevisiae | |
CH3-CH2-CH2-Hg | mercurials inhibit the hydrolysis of the good substrate benzyloxycarbonyl-L-Phe-L-Leu, the inhibition is repressed by the competitive inhibitors benzyloxycarbonyl-D-Phe-D-Leu-Leu-Phe, trans-cinnamate and acetyl-D-Phe ethyl ester. Aromatic, methyl and ethyl mercurials do not cause complete inactivation with the poor substrates benzyloxycarbonyl-Gly-Phe and benzoyl-Gly-beta,L-phenyllactate. Propyl and butyl-mercurials enhance these activities | Saccharomyces cerevisiae |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3-Phenyl-1-propanol | inhibits hydrolysis of benzyloxycarbonyl-Phe-Leu, activates hydrolysis of benzyloxycarbonyl-Gly-Phe | Saccharomyces cerevisiae | |
Hg2+ | - |
Saccharomyces cerevisiae | |
p-hydroxymercuribenzene sulfonate | mercurials inhibit the hydrolysis of the good substrate benzyloxycarbonyl-L-Phe-L-Leu, the inhibition is repressed by the competitive inhibitors benzyloxycarbonyl-D-Phe-D-Leu-Leu-Phe, trans-cinnamate and acetyl-D-Phe ethyl ester. Aromatic, methyl and ethyl mercurials do not cause complete inactivation with the poor substrates benzyloxycarbonyl-Gly-Phe and benzoyl-Gly-beta,L-phenyllactate. Propyl and butyl-mercurials enhance these activities | Saccharomyces cerevisiae | |
p-hydroxymercuribenzoate | mercurials inhibit the hydrolysis of the good substrate benzyloxycarbonyl-L-Phe-L-Leu, the inhibition is repressed by the competitive inhibitors benzyloxycarbonyl-D-Phe-D-Leu-Leu-Phe, trans-cinnamate and acetyl-D-Phe ethyl ester. Aromatic, methyl and ethyl mercurials do not cause complete inactivation with the poor substrates benzyloxycarbonyl-Gly-Phe and benzoyl-Gly-beta,L-phenyllactate. Propyl and butyl-mercurials enhance these activities | Saccharomyces cerevisiae |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | influence of mercurials | Saccharomyces cerevisiae |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
baker's yeast | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-Phe ethyl ester + H2O | - |
Saccharomyces cerevisiae | ? | - |
? | |
acetyl-Phe-Leu + H2O | - |
Saccharomyces cerevisiae | acetyl-Phe + Leu | - |
? | |
acetyl-Phe-NH2 + H2O | - |
Saccharomyces cerevisiae | ? | - |
? | |
benzoyl-Gly-beta-phenyllactate + H2O | poor substrate | Saccharomyces cerevisiae | ? | - |
? | |
Benzyloxycarbonyl-Gly-Phe + H2O | poor substrate | Saccharomyces cerevisiae | Benzyloxycarbonyl-Gly + Phe | - |
? | |
benzyloxycarbonyl-Phe-Gly + H2O | - |
Saccharomyces cerevisiae | benzyloxycarbonyl-Phe + Gly | - |
? | |
benzyloxycarbonyl-Phe-Leu + H2O | - |
Saccharomyces cerevisiae | benzyloxycarbonyl-Phe + Leu | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | influence of mercurials | Saccharomyces cerevisiae |