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Literature summary for 3.4.15.1 extracted from
- Angiotensin I-converting enzyme from guinea pig lung and serum. A comparison of some kinetic and inhibition properties (1976), Biochim. Biophys. Acta, 445, 161-168.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| angiotensin II | - |
Cavia porcellus |  |
| bradykinin | - |
Cavia porcellus | |
| concanavalin A | - |
Cavia porcellus | |
| EDTA | - |
Cavia porcellus | |
| pyrrolidone-Lys-Trp-Ala-Pro | - |
Cavia porcellus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.076 | - |
angiotensin I | serum enzyme | Cavia porcellus | |
| 0.078 | - |
angiotensin I | lung enzyme | Cavia porcellus | |
| 2.9 | - |
hippuryl-His-Leu | serum enzyme | Cavia porcellus | |
| 3.1 | - |
hippuryl-His-Leu | lung enzyme | Cavia porcellus | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| NaCl | required | Cavia porcellus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Cavia porcellus | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| side-chain modification | glycoprotein | Cavia porcellus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| lung | - |
Cavia porcellus | - |
| serum | - |
Cavia porcellus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| angiotensin I + H2O | - |
Cavia porcellus | angiotensin II + His-Leu | - |
? | |
| hippuryl-His-Leu + H2O | - |
Cavia porcellus | hippuric acid + His-Leu | - |
? | |
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