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Literature summary for 3.4.15.1 extracted from

  • Dorer, F.E.; Kahn, J.R.; Lentz, K.E.; Levine, M.; Skeggs, L.T.
    Kinetic properties of pulmonary angiotensin-converting enzyme. Hydrolysis of hippurylglycylglycine (1976), Biochim. Biophys. Acta, 429, 220-228.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
Cl-
-
Sus scrofa

Inhibitors

Inhibitors Comment Organism Structure
Arg-Pro-Pro more inhibitory at pH 8 than at pH 6 Sus scrofa
EDTA somewhat more effective at pH 6 than at pH 8 Sus scrofa
Glu-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro
-
Sus scrofa

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.9
-
hippuryl-Gly-Gly pH 6, 0.1 M NaCl Sus scrofa

Metals/Ions

Metals/Ions Comment Organism Structure
Co2+ activation Sus scrofa

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
hog
-

Source Tissue

Source Tissue Comment Organism Textmining
lung
-
Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
hippuryl-Gly-Gly + H2O
-
Sus scrofa hippuric acid + Gly-Gly
-
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