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Literature summary for 3.4.15.1 extracted from
- Kinetic properties of pulmonary angiotensin-converting enzyme. Hydrolysis of hippurylglycylglycine (1976), Biochim. Biophys. Acta, 429, 220-228.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| Cl- | - |
Sus scrofa |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Arg-Pro-Pro | more inhibitory at pH 8 than at pH 6 | Sus scrofa | |
| EDTA | somewhat more effective at pH 6 than at pH 8 | Sus scrofa | |
| Glu-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro | - |
Sus scrofa | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.9 | - |
hippuryl-Gly-Gly | pH 6, 0.1 M NaCl | Sus scrofa | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Co2+ | activation | Sus scrofa | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Sus scrofa | - |
hog | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| lung | - |
Sus scrofa | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| hippuryl-Gly-Gly + H2O | - |
Sus scrofa | hippuric acid + Gly-Gly | - |
? | |
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