Literature summary for 3.4.15.1 extracted from

Yokosawa, H.; Endo, S.; Ohgaki, Y.; Maeyama, J.; Ishii, S.
Hydrolysis of substance P and its analogs by angiotensin-converting enzyme from rat lung. Characterization of endopeptidase activity of the enzyme (1985), J. Biochem., 98, 1293-1299.

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Activating Compound

Activating Compound	Comment	Organism	Structure
Cl-	required	Rattus norvegicus

Inhibitors

Inhibitors	Comment	Organism	Structure
captopril	-	Rattus norvegicus
EDTA	-	Rattus norvegicus
MK-421	-	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
lung	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 + H2O	-	Rattus norvegicus	Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly + Leu-Met-NH2	-	?

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Release 2023.1 (January 2023)