Any feedback?
Literature summary for 3.4.15.1 extracted from
- Analysis of novel angiotensin I-converting enzyme inhibitory peptides from enzymatic hydrolysates of cuttlefish (Sepia officinalis) muscle proteins (2010), J. Agric. Food Chem., 58, 3840-3846.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Ala-Gly-Ser | - |
Homo sapiens |  |
| Ala-Gly-Ser-Pro | - |
Homo sapiens | |
| Ala-Gly-Ser-Ser | - |
Homo sapiens | |
| Ala-His-Ser-Tyr | a noncompetitive inhibitor, the peptide is resistant to further degenration by pepsin, trypsin, and chymotrypsin | Homo sapiens | |
| Ala-Val-Val | - |
Homo sapiens | |
| angiotensin I-converting enzyme inhibitory peptides | i.e. ACE-Is, from enzymatic hydrolysates of cuttlefish, Sepia officinalis, muscle proteins, generated by the crude enzyme from Bacillus mojavensis A21, show 87.11% inhibition at 2 mg/ml, mass spectrometric analysis, overview | Homo sapiens | |
| Asp-Phe-Gly | - |
Homo sapiens | |
| Gly-Asp-Ala-Pro | - |
Homo sapiens | |
| Gly-His-Gly | - |
Homo sapiens | |
| Gly-Val-His-His-Ala | - |
Homo sapiens | |
| Ile-Ala-Val | - |
Homo sapiens | |
| Phe-Gly-Gly | - |
Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| hippuryl-His-Leu + H2O | - |
Homo sapiens | hippuric acid + His-Leu | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ACE | - |
Homo sapiens |
| angiotensin I-converting enzyme | - |
Homo sapiens |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Homo sapiens |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.3 | - |
assay at | Homo sapiens |
IC50 Value
| IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|
| 0.0116 | - |
- |
Homo sapiens | Ala-His-Ser-Tyr | |
| 0.0225 | - |
- |
Homo sapiens | Gly-Asp-Ala-Pro | |
| 0.0372 | - |
- |
Homo sapiens | Ala-Gly-Ser-Pro | |
| 0.0447 | - |
- |
Homo sapiens | Asp-Phe-Gly | |
| 0.0666 | - |
- |
Homo sapiens | Ala-Val-Val | |
| 0.0718 | - |
- |
Homo sapiens | Gly-Val-His-His-Ala | |
| 0.0825 | - |
- |
Homo sapiens | Phe-Gly-Gly | |
| 0.122 | - |
- |
Homo sapiens | Gly-His-Gly | |
| 0.1534 | - |
- |
Homo sapiens | Ile-Ala-Val | |
| 0.5279 | - |
- |
Homo sapiens | Ala-Gly-Ser | |
| 0.672 | - |
- |
Homo sapiens | Ala-Gly-Ser-Ser | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
