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Literature summary for 3.4.15.1 extracted from

  • Lambert, D.W.; Clarke, N.E.; Hooper, N.M.; Turner, A.J.
    Calmodulin interacts with angiotensin-converting enzyme-2 (ACE2) and inhibits shedding of its ectodomain (2008), FEBS Lett., 582, 385-390.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens angiotensin-converting enzyme-2 is a regulatory protein of the renin-angiotensin system. ACE2 interacts with calmodulin and this association down-regulates shedding of the ACE2 ectodomain ?
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?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HEK-293 cell stably transfected with full-length ACE2 Homo sapiens
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Huh-7 cell endogenously expressing ACE2 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information angiotensin-converting enzyme-2 is a regulatory protein of the renin-angiotensin system. ACE2 interacts with calmodulin and this association down-regulates shedding of the ACE2 ectodomain Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
ACE2
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Homo sapiens
angiotensin-converting enzyme-2
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Homo sapiens