Literature summary for 3.4.15.1 extracted from

Goossens, G.H.; Blaak, E.E.; Schiffers, P.M.; Saris, W.H.; Baak, M.A.
Effect of short-term ACE inhibitor treatment on peripheral insulin sensitivity in obese insulin-resistant subjects (2006), Diabetologia, 49, 3009-3016.

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Application

Application	Comment	Organism
medicine	short-term ramipril treatment adequately reduces angiotensin-converting enzyme activity and blood pressure, but has no significant effects on insulin sensitivity, forearm blood flow, substrate fluxes across the forearm, whole-body substrate oxidation and intramuscular triacylglycerol content in obese insulinresistant subjects	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
ramipril	short-term ramipril treatment adequately reduces angiotensin-converting enzyme activity and blood pressure, but has no significant effects on insulin sensitivity, forearm blood flow, substrate fluxes across the forearm, whole-body substrate oxidation and intramuscular triacylglycerol content in obese insulinresistant subjects	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

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Release 2023.1 (January 2023)