Literature summary for 3.4.15.1 extracted from

Oyama, N.; Urasawa, K.; Kaneta, S.; Sakai, H.; Saito, T.; Takagi, C.; Yoshida, I.; Kitabatake, A.; Tsutsui, H.
Angiotensin converting enzyme inhibitors attenuated the expression of G-protein coupled receptor kinases in heart failure patients (2006), Circ. J., 70, 362-363.

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Application

Application	Comment	Organism
medicine	the expression level of G-protein coupled receptor kinase mRNA shows the severity of CHF. Angiotensin converting enzyme inhibitor abolishes the enhanced expression of G-protein coupled receptor kinase. Angiotensin converting enzyme inhibitor mediated transcriptional regulation of G-protein coupled receptor kinase gene documents a mechanism of beta-adrenergic receptor regulation, and may provide, at least in part, a potential mechanism responsible for the beneficial effect of angiotensin converting enzyme inhibitor in the treatment of congestive heart failure	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	patients with congestive heart failure	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

Synonyms

Synonyms	Comment	Organism
ACEI	-	Homo sapiens
angiotensin converting enzyme inhibitor	-	Homo sapiens

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Release 2023.1 (January 2023)