Literature summary for 3.4.15.1 extracted from

Corradi, H.R.; Chitapi, I.; Sewell, B.T.; Georgiadis, D.; Dive, V.; Sturrock, E.D.; Acharya, K.R.
The structure of testis angiotensin-converting enzyme in complex with the C domain-specific inhibitor RXPA380 (2007), Biochemistry, 46, 5473-5478.

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Crystallization (Commentary)

Crystallization (Comment)	Organism
hanging drop method, crystal structure at a resolution of 2.25 A of testis enzyme with the highly C-domain-specific phosphinic inhibitor, RXPA380	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
2-[([2-[(1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl)(hydroxy)phosphoryl]cyclopentyl]carbonyl)amino]-3-(2,3-dihydro-1H-indol-3-yl)propanoate	-	Homo sapiens
RXPA380	C domain-specific inhibitor	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P12821	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Homo sapiens

Source Tissue

Source Tissue	Comment	Organism	Textmining
testis	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
hippuryl-histidyl-leucine + H2O	-	Homo sapiens	?	-	?

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Release 2023.1 (January 2023)