Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.15.1 extracted from

  • Saiga, A.; Okumura, T.; Makihara, T.; Katsuda, S.; Morimatsu, F.; Nishimura, T.
    Action mechanism of an angiotensin I-converting enzyme inhibitory peptide derived from chicken breast muscle (2006), J. Agric. Food Chem., 54, 942-945.
    View publication on PubMed
Search for more literature for 3.4.15.1

Inhibitors

Inhibitors Comment Organism Structure
Gly-Phe-Hyp-Gly-Thr-Hyp-Gly-Leu-Hyp-Gly-Phe IC50: 0.026 mM. Inhibitory peptide derived from chicken breast muscle Oryctolagus cuniculus
Gly-Phe-Hyp-Gly-Thr-Hyp-Gly-Leu-Hyp-Gly-Phe inhibitory peptide derived from chicken breast muscle possesses hypotensive activity for spontaneously hypertensive rats Rattus norvegicus
Hyp-Gly-Leu-Hyp-Gly-Phe 0.01 mM Oryctolagus cuniculus
Hyp-Gly-Phe IC50: 0.433 mM Oryctolagus cuniculus
Hyp-Gly-Thr-Hyp-Gly-Leu-Hyp-Gly-Phe 0.019 mM Oryctolagus cuniculus
Phe-Hyp-Gly IC50: 0.171 mM Oryctolagus cuniculus
Phe-Hyp-Gly-Thr-Hyp-Gly 0.406 mM Oryctolagus cuniculus
Phe-Hyp-Gly-Thr-Hyp-Gly-Leu-Hyp-Gly 25 mM Oryctolagus cuniculus

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
lung
-
 Oryctolagus cuniculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
hippuryl-His-Leu + H2O
-
 Oryctolagus cuniculus hippuric acid + His-Leu
-
 ?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.01148
-
 Gly-Phe-Hyp-Gly-Thr-Hyp-Gly-Leu-Hyp-Gly-Phe 37°C, pH 8.3 Oryctolagus cuniculus

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.026
-
 IC50: 0.026 mM. Inhibitory peptide derived from chicken breast muscle Oryctolagus cuniculus Gly-Phe-Hyp-Gly-Thr-Hyp-Gly-Leu-Hyp-Gly-Phe
0.171
-
 IC50: 0.171 mM Oryctolagus cuniculus Phe-Hyp-Gly
0.433
-
 IC50: 0.433 mM Oryctolagus cuniculus Hyp-Gly-Phe