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Literature summary for 3.4.14.9 extracted from

  • Kim, K.H.; Pham, C.T.; Sleat, D.E.; Lobel, P.
    Dipeptidyl-peptidase I does not functionally compensate for the loss of tripeptidyl-peptidase I in the neurodegenerative disease late-infantile neuronal ceroid lipofuscinosis (2008), Biochem. J., 415, 225-232.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.14.9

Localization

Localization Comment Organism GeneOntology No. Textmining
lysosome
-
 Mus musculus 5764
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus dipeptidyl-peptidase I cannot functionally compensate for the loss of tripeptidyl-peptidase I ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain TPPI is expressed ubiquitously throughout the body but disease appears restricted to the brain Mus musculus
-
heart
-
 Mus musculus
-
kidney highest activity in kidney Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Ala-L-Ala-L-Phe-7-amido-4-methylcoumarin + H2O
-
 Mus musculus L-Ala-L-Ala-L-Phe + 7-amino-4-methylcoumarin
-
 ?
additional information dipeptidyl-peptidase I cannot functionally compensate for the loss of tripeptidyl-peptidase I Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
TPPI
-
 Mus musculus
tripeptidyl peptidase I
-
 Mus musculus