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Literature summary for 3.4.14.5 extracted from

  • Dimitrova, M.; Ivanov, I.; Todorova, R.; Stefanova, N.; Moskova-Doumanova, V.; Topouzova-Hristova, T.; Saynova, V.; Stephanova, E.
    Comparison of the activity levels and localization of dipeptidyl peptidase IV in normal and tumor human lung cells (2012), Tissue Cell, 44, 74-79.
    View publication on PubMed
Search for more literature for 3.4.14.5

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane in P and A549 cells the enzyme is associated with the plasmalemma while in SK-MES-1 cells it is bound to intracellular membranes Homo sapiens 16020
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outer membrane in P and A549 cells the enzyme is associated with the plasmalemma while in SK-MES-1 cells it is bound to intracellular membranes Homo sapiens 19867
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
A-549 cell
-
 Homo sapiens
-
lung fetal lung-derived cells. Surface and total dipeptidyl peptidase activities of P cells are correspondingly 7-8 and 3-10 times higher than those of SK-MES-1 and A549 cells Homo sapiens
-
SK-MES-1 cell
-
 Homo sapiens
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squamous cell carcinoma cell squamous lung carcinoma, enzymic activity is restricted to the connective tissue stroma surrounding the dipeptidyl peptidase IV-negative tumor foci Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-(glycyl-L-prolyl hydrazido)-N-hexyl-1,8-naphthalimide + H2O
-
 Homo sapiens ?
-
 ?
glycyl-L-prolyl-4-nitroanilide + H2O
-
 Homo sapiens Gly-L-Pro + 4-nitroaniline
-
 ?