Inhibitors | Comment | Organism | Structure |
---|---|---|---|
vildagliptin | vildagliptin improves glucose tolerance and increases the beta-cell mass by reducing beta-cell apoptosis in Insulin Receptor Substrate-2-Knockout mice fed a high-fat diet, and the reduction of beta-cell apoptosis by vildagliptin is independent of the Insulin Receptor Substrate-2 expression in the cells | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | P28843 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
dipeptidyl peptidase-4 | - |
Mus musculus |
DPP-4 | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
physiological function | inhibition of enzyme by vildagliptin improves glucose tolerance and increases the beta-cell mass by reducing beta-cell apoptosis in Insulin Receptor Substrate-2-knockout mice fed a high-fat diet, and the reduction of beta-cell apoptosis by vildagliptin is independent of the Insulin Receptor Substrate-2 expression in the cells | Mus musculus |