Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.14.5 extracted from

  • Alponti, R.F.; Frezzatti, R.; Barone, J.M.; Alegre, V.D.; Silveira, P.F.
    Dipeptidyl peptidase IV in the hypothalamus and hippocampus of monosodium glutamate obese and food-deprived rats (2011), Metab. Clin. Exp., 60, 234-242.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Diprotin A dipeptidyl peptidase IV in soluble and membrane-bound fractions from the hypothalamus and hippocampus areas is distinguished kinetically as insensitive and sensitive to diprotin A, respectively Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
beta-endorphin + H2O Rattus norvegicus
-
?
-
?
neuropeptide Y + H2O Rattus norvegicus
-
?
-
?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus P14740
-
-

Source Tissue

Source Tissue Comment Organism Textmining
hippocampus
-
Rattus norvegicus
-
hypothalamus
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
beta-endorphin + H2O
-
Rattus norvegicus ?
-
?
Gly-L-Pro-4-methoxy-beta-naphthylamide + H2O
-
Rattus norvegicus Gly-L-Pro + 4-methoxy-beta-naphthylamine
-
?
neuropeptide Y + H2O
-
Rattus norvegicus ?
-
?

Synonyms

Synonyms Comment Organism
CD26
-
Rattus norvegicus
dipeptidyl peptidase IV
-
Rattus norvegicus
DPPIV
-
Rattus norvegicus

Expression

Organism Comment Expression
Rattus norvegicus monosodium glutamate and/or food deprivation decreases the activity of DPPIV insensitive to diprotin A in the soluble and membrane-bound fraction from the hypothalamus, as well as the activity of DPPIV sensitive to diprotin A in the soluble fraction from the hypothalamus and in the membrane-bound fraction from the hippocampus down
Rattus norvegicus monosodium glutamate and/or food deprivation increases the activity of DPPIV insensitive to diprotin A in the membrane-bound fraction from the hippocampus up