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Literature summary for 3.4.14.5 extracted from

  • Boschmann, M.; Engeli, S.; Dobberstein, K.; Budziarek, P.; Strauss, A.; Boehnke, J.; Sweep, F.C.; Luft, F.C.; He, Y.; Foley, J.E.; Jordan, J.
    Dipeptidyl-peptidase-IV inhibition augments postprandial lipid mobilization and oxidation in type 2 diabetic patients (2009), J. Clin. Endocrinol. Metab., 94, 846-852.
    View publication on PubMed

Application

Application Comment Organism
medicine DPP-4 inhibition augments postprandial lipid mobilization and oxidation and increases endogenous glucagon-like peptide 1 activity, resulting in improved glycemic control in patients with type 2 diabetes mellitus Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
vildagliptin potent, selective DPP-4 inhibitor Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
glucagon-like peptide 1 + H2O Homo sapiens
-
?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glucagon-like peptide 1 + H2O
-
Homo sapiens ?
-
?
Gly-L-Pro-7-amido-4-methylcoumarin + H2O
-
Homo sapiens Gly-L-Pro + 7-amino-4-methylcoumarin
-
?

Synonyms

Synonyms Comment Organism
dipeptidyl peptidase-IV
-
Homo sapiens
DPP-4
-
Homo sapiens