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Literature summary for 3.4.14.5 extracted from
- DPP-4 inhibition improves glucose tolerance and increases insulin and GLP-1 responses to gastric glucose in association with normalized islet topography in mice with beta-cell-specific overexpression of human islet amyloid polypeptide (2007), Regul. Pept., 143, 97-103.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | DPP-4 inhibition increases active glucagon-like peptide 1 levels and improves glucose tolerance and islet function with improved islet topography in mice with a beta-cellspecific overexpression of human islet amyloid peptide. These findings support the potential value of DPP-4 inhibition in the treatment of diabetes with the potential of normalizing islet function | Mus musculus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| vildagliptin | - |
Mus musculus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| DPP-4 | - |
Mus musculus |
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