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Literature summary for 3.4.14.5 extracted from

  • He, Y.L.; Ligueros-Saylan, M.; Sunkara, G.; Sabo, R.; Zhao, C.; Wang, Y.; Campestrini, J.; Pommier, F.; Dole, K.; Marion, A.; Dole, W.P.; Howard, D.
    Vildagliptin, a novel dipeptidyl peptidase IV inhibitor, has no pharmacokinetic interactions with the antihypertensive agents amlodipine, valsartan, and ramipril in healthy subjects (2008), J. Clin. Pharmacol., 48, 85-95.
    View publication on PubMed

Application

Application Comment Organism
medicine vildagliptin is a dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes. No adjustment in dosage based on pharmacokinetic considerations is required should vildagliptin be coadministered with amlodipine, valsartan, or ramipril in patients with type 2 diabetes and hypertension Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
vildagliptin
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-