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Literature summary for 3.4.14.5 extracted from

  • Cejkova, J.; Zvarova, Z.; Cejka, C.
    Dipeptidyl peptidase IV (DPPIV) activity in the tear fluid as an indicator of the severity of corneal injury: a histochemical and biochemical study (2004), Histol. Histopathol., 19, 669-676.
    View publication on PubMed

Application

Application Comment Organism
diagnostics the activity of DPPIV measured in the tear fluid might serve as an indicator of early corneal disorders, e.g.corneal vascularization related to contact lens wear Oryctolagus cuniculus

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
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-
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Source Tissue

Source Tissue Comment Organism Textmining
cornea in contrast to the normal cornea where DPPIV activity is absent and the tear fluid where it is low, during continuous wearing of contact lenses or repeated irradiation of the cornea with UVB rays, slight DPPIV activity appeared first in the superficial layers of the corneal epithelium, while later increased activity is present in the whole epithelium.This parallels elevated DPPIV activity in the tear fluid Oryctolagus cuniculus
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tear in contrast to the normal cornea where DPPIV activity is absent and the tear fluid where it is low, during continuous wearing of contact lenses or repeated irradiation of the cornea with UVB rays, slight DPPIV activity appeared first in the superficial layers of the corneal epithelium, while later increased activity is present in the whole epithelium.This parallels elevated DPPIV activity in the tear fluid Oryctolagus cuniculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Gly-Pro-7-amido-4-trifluoromethyl coumarin + H2O
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Oryctolagus cuniculus Gly-Pro + 7-amino-4-trifluoromethyl coumarin
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?

Synonyms

Synonyms Comment Organism
DPPIV
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Oryctolagus cuniculus