Application | Comment | Organism |
---|---|---|
pharmacology | target for development of selective inhibitors for control of the enzyme's biological function | Homo sapiens |
Crystallization (Comment) | Organism |
---|---|
X-ray diffraction strcuture determination at 2.6 A resolution | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | enzyme is implicated in several diseases | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
release of an N-terminal dipeptide, Xaa-Yaa-/-Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline | serine protease | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | enzyme is implicated in several diseases | Homo sapiens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | enzyme possesses a unique eight-bladed beta-propeller fold | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
dipeptidyl peptidase IV | - |
Homo sapiens |
DPPIV | - |
Homo sapiens |
More | enzyme belongs to the prolyl oligopeptidase POP family | Homo sapiens |