Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Gly-Gly-Phe-Leu | enkephalin fragment | Homo sapiens | |
Leu-Val-Val-Tyr-Pro-Trp-Thr-Gln-Arg | Leu-valorphin-Arg | Homo sapiens | |
Tyr(SO3H)-Gly-Gly-Phe-Leu | - |
Homo sapiens | |
Tyr-Ala-Gly-Phe-Leu | Ala2-Leu-enkephalin | Homo sapiens | |
Tyr-D-Ala-Gly-Phe-Leu | D-Ala2-Leu-enkephalin | Homo sapiens | |
Tyr-Gly-Gly-Phe | enkephalin fragment | Homo sapiens | |
Tyr-Gly-Gly-Phe-Leu | Leu-enkephalin | Homo sapiens | |
Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile | dynorphin A 1-8 | Homo sapiens | |
Tyr-Pro-Phe-Phe-NH2 | endomorphin-2 | Homo sapiens | |
Tyr-Pro-Phe-Val-Glu-Pro-Ile | human beta-casomorphin | Homo sapiens | |
Tyr-Pro-Trp-Phe-NH2 | endomorphin-1 | Homo sapiens | |
Val-Val-Tyr-Pro-Trp-Thr-Gln | valorphin | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0081 | - |
Tyr-Pro-Trp-Phe-NH2 | endomorphin-1 | Homo sapiens | |
0.0222 | - |
Arg-Arg-2-naphthylamide | - |
Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | - |
Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
82000 | - |
determined by PAGE, native and denaturing conditions | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
the protein is purified from human erythrocytes | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cerebrospinal fluid | - |
Homo sapiens | - |
erythrocyte | - |
Homo sapiens | - |
spinal cord | superficial laminae of the spinal cord dorsal horn | Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
87.5 | - |
in the presence of 10 microM CoCl2 | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Arg-Arg-2-naphthylamide + H2O | substrate used in the activity assay | Homo sapiens | Arg-Arg + 2-naphthylamine | - |
? | |
Tyr-Pro-Trp-Phe-NH2 + H2O | endomorphin-1 | Homo sapiens | Tyr-Pro + Trp-Phe-NH2 | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | - |
Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
dipeptidyl arylamidase III | - |
Homo sapiens |
dipeptidyl peptidase III | - |
Homo sapiens |
DPP III | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
- |
Homo sapiens |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
2 | 8 | Arg-Arg-2-naphthylamide | - |
Homo sapiens | |
5 | - |
Tyr-Pro-Trp-Phe-NH2 | endomorphin-1 | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
physiological condition, determination of Ki values and kinetic parameters of the hydrolysis of endomorphin-1 | Homo sapiens |
8.6 | - |
assay condition with the synthetic substrate Arg-Arg-2-naphthylamide, determination of specific activity | Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.000049 | - |
Val-Val-Tyr-Pro-Trp-Thr-Gln | - |
Homo sapiens | |
0.000375 | - |
Tyr-Ala-Gly-Phe-Leu | - |
Homo sapiens | |
0.00056 | - |
Tyr-Pro-Phe-Val-Glu-Pro-Ile | - |
Homo sapiens | |
0.00249 | - |
Tyr-Pro-Phe-Phe-NH2 | - |
Homo sapiens | |
0.00341 | - |
Leu-Val-Val-Tyr-Pro-Trp-Thr-Gln-Arg | - |
Homo sapiens | |
0.00365 | - |
Tyr-Gly-Gly-Phe-Leu | - |
Homo sapiens | |
0.004 | - |
Tyr-Gly-Gly-Phe | - |
Homo sapiens | |
0.005 | - |
Tyr-Pro-Trp-Phe-NH2 | - |
Homo sapiens | |
0.0235 | - |
Gly-Gly-Phe-Leu | - |
Homo sapiens | |
0.027 | - |
Tyr-D-Ala-Gly-Phe-Leu | - |
Homo sapiens | |
0.0434 | - |
Tyr(SO3H)-Gly-Gly-Phe-Leu | - |
Homo sapiens | |
0.0699 | - |
Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile | - |
Homo sapiens |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Homo sapiens | - |
- |
4.5 |