Literature summary for 3.4.14.4 extracted from

Fukasawa, K.; Fukasawa, K.M.; Kanai, M.; Fujii, S.; Hirose, J.; Harada, M.
Dipeptidyl peptidase III is a zinc metallo-exopeptidase (1998), Biochem. J., 329, 275-282.

Search for more literature for 3.4.14.4

Protein Variants

Protein Variants	Comment	Organism
H450Y	no activity	Homo sapiens
H455Y	no activity	Homo sapiens
Q451A	no activity	Homo sapiens
Q451D	no activity	Homo sapiens
Q508A	no activity	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
3,4-dichloroisocoumarin	-	Homo sapiens
EDTA	-	Homo sapiens
p-chloromercuriphenylsulfonic acid	-	Homo sapiens

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.3	-	Arg-Arg-2-naphthylamide	-	Homo sapiens

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Zn2+	contains 1 mol of Zn2+ per mol of enzyme	Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
93000	-	gel filtration	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Homo sapiens

Source Tissue

Source Tissue	Comment	Organism	Textmining
placenta	-	Homo sapiens	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
14.2	-	-	Homo sapiens

Storage Stability

Storage Stability	Organism
-20°C, 50% glycerol, 1 year	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
Arg-Arg-2-naphthylamide + H2O	-	Homo sapiens	Arg-Arg + 2-naphthylamine	-	?
Lys-Ala-2-naphthylamide + H2O	-	Homo sapiens	Lys-Ala + 2-naphthylamine	-	?

Subunits

Subunits	Comment	Organism
monomer	1 * ?, SDS-PAGE	Homo sapiens

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
8.8	-	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)