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Literature summary for 3.4.14.2 extracted from

  • McDonald, J.K.; Schwabe, C.
    Dipeptidyl peptidase II of bovine dental pulp. Initial demonstration and characterization as a fibroblastic, lysosomal peptidase of the serine class active on collagen-related peptides (1980), Biochim. Biophys. Acta, 616, 68-81.
    View publication on PubMed
Search for more literature for 3.4.14.2

Inhibitors

Inhibitors Comment Organism Structure
4-Chloromercuriphenylsulfonate
-
 Bos taurus
Hg2+ HgCl2 Bos taurus
hyamine 10-X
-
 Bos taurus
Lys-Ala chloromethyl ketone 0.1 mM, complete inhibition, active-site-directed inhibitor Bos taurus
Na+
-
 Bos taurus
p-Nitrophenyl-p-guanidinobenzoate
-
 Bos taurus
puromycin
-
 Bos taurus
Tris
-
 Bos taurus

Localization

Localization Comment Organism GeneOntology No. Textmining

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
dental pulp
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Lys-Ala-2-naphthylamide + H2O
-
 Bos taurus Lys-Ala + 2-naphthylamine
-
 ?
Lys-Ala-Ala + H2O
-
 Bos taurus Lys-Ala + Ala
-
 ?
Lys-Ala-Pro + H2O
-
 Bos taurus Lys-Ala + Pro
-
 ?
Lys-Pro-2-(4-methoxy)-naphthylamide + H2O
-
 Bos taurus ?
-
 ?
Lys-Pro-2-naphthylamide + H2O
-
 Bos taurus Lys-Pro + 2-naphthylamine
-
 ?
additional information Pro and Arg are the preferred penultimate residues Bos taurus ?
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
4.2 5.3 hydrolysis of tripeptides Bos taurus
5 5.7 hydrolysis of 2-naphthylamide derivatives Bos taurus