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Literature summary for 3.4.14.2 extracted from

  • DiCarlantonio, G.; Talbot, P.; Dudenhausen, E.
    Partial purification and characterization of dipeptidyl peptidase II (DPP II) from guinea pig testes (1986), Gamete Res., 15, 161-175.
No PubMed abstract available
Search for more literature for 3.4.14.2

Inhibitors

Inhibitors Comment Organism Structure
Cu2+ 10 mM CuSO4, 23% inhibition Cavia porcellus
K+ 50 mM KCl, 42% inhibition Cavia porcellus
Na+ 10 mM NaCl, 38% inhibition Cavia porcellus
p-Nitrophenyl-p-guanidinobenzoate 1 mM, 43% inhibition Cavia porcellus
phenylmethylsulfonyl fluoride 1 mM, 15% inhibition Cavia porcellus
Tris 50 mM, 97% inhibition Cavia porcellus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
135000
-
 gel filtration Cavia porcellus

Organism

Organism UniProt Comment Textmining
Cavia porcellus
-
 multiple isoforms
-

Purification (Commentary)

Purification (Comment) Organism
partial, multiple isoforms Cavia porcellus

Source Tissue

Source Tissue Comment Organism Textmining
testis
-
 Cavia porcellus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
27.4
-
-
 Cavia porcellus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(Ala)3 + H2O
-
 Cavia porcellus ?
-
 ?
Lys-Ala-2-(4-methoxy)-naphthylamide Lys-Ala-4-methoxy-2-naphthylamide + H2O
-
 Cavia porcellus ?
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 64000-66000, SDS-PAGE Cavia porcellus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
4.5
-
 hydrolysis of (Ala)3 Cavia porcellus

pH Range

pH Minimum pH Maximum Comment Organism
3.7 5.8 pH 3.5: about 85% of maximal activity, pH 5.8: about 45% of maximal activity Cavia porcellus