Any feedback?
Literature summary for 3.4.14.10 extracted from
- Role of tripeptidyl peptidase II in the processing of Listeria monocytogenes-derived MHC class I-presented antigenic peptides (2009), Microbes Infect., 11, 795-802.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Ala-Ala-Phe-CMK | - |
Mus musculus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| spleen | CD8 T cell lines specific are generated from spleen cells from Listeria monocytogenes-infected BALB/c mice 2 weeks after infection | Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Ala-Ala-Phe-7-amido-4-methylcoumarin + H2O | - |
Mus musculus | Ala-Ala-Phe + 7-amino-4-methylcoumarin | - |
? | |
| N-succinyl-Leu-Leu-Val-Tyr-7-amido-4-methylcoumarin + H2O | - |
Mus musculus | N-succinyl-Leu-Leu-Val-Tyr + 7-amino-4-methylcoumarin | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| TPPII | - |
Mus musculus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Mus musculus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.8 | - |
assay at | Mus musculus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | it is demonstrated that both, the proteasome and TPPII play a role in the processing of Listeria monocytogenes-derived antigenic peptides | Mus musculus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
