Any feedback?
Literature summary for 3.4.14.10 extracted from
- Viability and DNA damage responses of TPPII-deficient Myc- and Ras-transformed fibroblasts (2009), Biochem. Biophys. Res. Commun., 386, 563-568.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Mus musculus | 5829 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | Q64514 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| fibroblast | - |
Mus musculus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| TPPII | - |
Mus musculus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | cell lines from primary fibroblasts are generated having conditional (floxed) TPPII alleles, transformed with both the c-myc and H-ras oncogenes. TPPII is deleted using retroviral self-deleting Cre recombinase. Clonally derived TPPIIflox/flox and TPPII-/- transformed fibroblasts show no influences of TPPII expression on basal cell survival and proliferation, nor on radiation-induced p53 activation, p21 induction, cell cycle arrest, apoptosis, or clonogenic cell death | Mus musculus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
