Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli JM109(pTD-lac-NdeI-PTPA-L2R1) cells | Porphyromonas gingivalis |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | PTP-A is secreted to the surface of the outer membrane | Porphyromonas gingivalis | 16020 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
76000 | - |
SDS-PAGE | Porphyromonas gingivalis |
80000 | - |
mature enzyme, estimated from amino acid sequence | Porphyromonas gingivalis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Porphyromonas gingivalis | PTP-A cleaves Xaa-Xaa-Pro-Yaa-(Xaa)n between Pro and Yaa, where Yaa represents any residue except proline, and Zaa represents any residue except glycine, proline, or a charged residue | ? | - |
? | |
additional information | Porphyromonas gingivalis W83 | PTP-A cleaves Xaa-Xaa-Pro-Yaa-(Xaa)n between Pro and Yaa, where Yaa represents any residue except proline, and Zaa represents any residue except glycine, proline, or a charged residue | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Porphyromonas gingivalis | - |
- |
- |
Porphyromonas gingivalis W83 | - |
- |
- |
Purification (Comment) | Organism |
---|---|
DEAE Sephacel column chromatography and hydroxyapatite column chromatography | Porphyromonas gingivalis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-Ala-L-Phe-L-Pro-p-nitroanilide + H2O | - |
Porphyromonas gingivalis | L-Ala-L-Phe-L-Pro + p-nitroaniline | - |
? | |
L-Ala-L-Phe-L-Pro-p-nitroanilide + H2O | - |
Porphyromonas gingivalis W83 | L-Ala-L-Phe-L-Pro + p-nitroaniline | - |
? | |
additional information | PTP-A cleaves Xaa-Xaa-Pro-Yaa-(Xaa)n between Pro and Yaa, where Yaa represents any residue except proline, and Zaa represents any residue except glycine, proline, or a charged residue | Porphyromonas gingivalis | ? | - |
? | |
additional information | PTP-A cleaves Xaa-Xaa-Pro-Yaa-(Xaa)n between Pro and Yaa, where Yaa represents any residue except proline, and Zaa represents any residue except glycine, proline, or a charged residue | Porphyromonas gingivalis W83 | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PTP-A | - |
Porphyromonas gingivalis |
tripeptidyl aminopeptidase | - |
Porphyromonas gingivalis |