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Literature summary for 3.4.14.10 extracted from

  • Oda, H.; Saiki, K.; Tonosaki, M.; Yajima, A.; Konishi, K.
    Participation of the secreted dipeptidyl and tripeptidyl aminopeptidases in asaccharolytic growth of Porphyromonas gingivalis (2008), J. Periodont. Res., 44, 362-267.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli JM109(pTD-lac-NdeI-PTPA-L2R1) cells Porphyromonas gingivalis

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane PTP-A is secreted to the surface of the outer membrane Porphyromonas gingivalis 16020
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
76000
-
SDS-PAGE Porphyromonas gingivalis
80000
-
mature enzyme, estimated from amino acid sequence Porphyromonas gingivalis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Porphyromonas gingivalis PTP-A cleaves Xaa-Xaa-Pro-Yaa-(Xaa)n between Pro and Yaa, where Yaa represents any residue except proline, and Zaa represents any residue except glycine, proline, or a charged residue ?
-
?
additional information Porphyromonas gingivalis W83 PTP-A cleaves Xaa-Xaa-Pro-Yaa-(Xaa)n between Pro and Yaa, where Yaa represents any residue except proline, and Zaa represents any residue except glycine, proline, or a charged residue ?
-
?

Organism

Organism UniProt Comment Textmining
Porphyromonas gingivalis
-
-
-
Porphyromonas gingivalis W83
-
-
-

Purification (Commentary)

Purification (Comment) Organism
DEAE Sephacel column chromatography and hydroxyapatite column chromatography Porphyromonas gingivalis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Ala-L-Phe-L-Pro-p-nitroanilide + H2O
-
Porphyromonas gingivalis L-Ala-L-Phe-L-Pro + p-nitroaniline
-
?
L-Ala-L-Phe-L-Pro-p-nitroanilide + H2O
-
Porphyromonas gingivalis W83 L-Ala-L-Phe-L-Pro + p-nitroaniline
-
?
additional information PTP-A cleaves Xaa-Xaa-Pro-Yaa-(Xaa)n between Pro and Yaa, where Yaa represents any residue except proline, and Zaa represents any residue except glycine, proline, or a charged residue Porphyromonas gingivalis ?
-
?
additional information PTP-A cleaves Xaa-Xaa-Pro-Yaa-(Xaa)n between Pro and Yaa, where Yaa represents any residue except proline, and Zaa represents any residue except glycine, proline, or a charged residue Porphyromonas gingivalis W83 ?
-
?

Synonyms

Synonyms Comment Organism
PTP-A
-
Porphyromonas gingivalis
tripeptidyl aminopeptidase
-
Porphyromonas gingivalis