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Literature summary for 3.4.14.10 extracted from

  • Bhutani, N.; Venkatraman, P.; Goldberg, A.L.
    Puromycin-sensitive aminopeptidase is the major peptidase responsible for digesting polyglutamine sequences released by proteasomes during protein degradation (2007), EMBO J., 26, 1385-1396.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.14.10

Inhibitors

Inhibitors Comment Organism Structure
butabindide specific TPPII inhibitor Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Homo sapiens 5829
-

Organism

Organism UniProt Comment Textmining
Homo sapiens P29144
-
-

Purification (Commentary)

Purification (Comment) Organism
DEAE column chromatography and Resource RPC hydrophobic column chromatography Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
HeLa cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Ala-Ala-Phe-7-amido-4-methylcoumarin + H2O
-
 Homo sapiens Ala-Ala-Phe + 7-amino-4-methylcoumarin
-
 ?
Gln-7-amido-4-methylcoumarin + H2O
-
 Homo sapiens Gln + 7-amino-4-methylcoumarin
-
 ?
KKE-5-[(2-aminoethyl) amino]-naphthalene-1-sulfonic acid-Q9K-4'-dimethylaminoazobenzene-4'-sulfonyl + H2O
-
 Homo sapiens ?
-
 ?
additional information no activity against Q20RRGRR and KKQ30KK Homo sapiens ?
-
 ?
Q20RRGRR + H2O little activity Homo sapiens Q17RRGRR + Q14RRGRR + QQQ
-
 ?

Synonyms

Synonyms Comment Organism
TPII
-
 Homo sapiens
tripeptidyl peptidase
-
 Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
-
 Homo sapiens