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Literature summary for 3.4.14.1 extracted from

  • Mallen-St Clair, J.; Pham, C.T.; Villalta, S.A.; Caughey, G.H.; Wolters, P.J.
    Mast cell dipeptidyl peptidase I mediates survival from sepsis (2004), J. Clin. Invest., 113, 628-634.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine mast cell DPPI harms the septic host. DPPI is a novel potential therapeutic target for treatment of sepsis Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus DPPI activates granule-associated serine proteases, several of which play important roles in host responses to bacterial infection. DPPI is a key regulator of survival from septic peritonitis ?
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?

Organism

Organism UniProt Comment Textmining
Mus musculus
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
mast cell bone marrow mast cell Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information DPPI activates granule-associated serine proteases, several of which play important roles in host responses to bacterial infection. DPPI is a key regulator of survival from septic peritonitis Mus musculus ?
-
?

Synonyms

Synonyms Comment Organism
DPPI
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Mus musculus