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Literature summary for 3.4.13.9 extracted from

  • Are, V.; Kumar, A.; Goyal, V.; Gotad, S.; Ghosh, B.; Gadre, R.; Jamdar, S.; Makde, R.
    Structures and activities of widely conserved small prokaryotic aminopeptidases-P clarify classification of M24B peptidases (2018), Proteins, 87, 212-225 .
    View publication on PubMed
Search for more literature for 3.4.13.9

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.91
-
 Met-Ala-Ala pH 7.0, 97°C, recombinant wild-type Pyrococcus furiosus
1.8
-
 Met-Pro-Ala pH 7.0, 97°C, recombinant wild-type Pyrococcus furiosus
9.8
-
 Met-Pro pH 7.0, 97°C, recombinant wild-type Pyrococcus furiosus

Metals/Ions

Metals/Ions Comment Organism Structure
Co2+ required Pyrococcus furiosus

Organism

Organism UniProt Comment Textmining
Pyrococcus furiosus P81535
-
-
Pyrococcus furiosus ATCC 43587 P81535
-
-
Pyrococcus furiosus JCM 8422 P81535
-
-
Pyrococcus furiosus Vc1 P81535
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Met-Ala-Ala + H2O
-
 Pyrococcus furiosus Met + Ala-Ala
-
 ?
Met-Ala-Ala + H2O
-
 Pyrococcus furiosus ATCC 43587 Met + Ala-Ala
-
 ?
Met-Ala-Ala + H2O
-
 Pyrococcus furiosus Vc1 Met + Ala-Ala
-
 ?
Met-Ala-Ala + H2O
-
 Pyrococcus furiosus JCM 8422 Met + Ala-Ala
-
 ?
Met-Pro + H2O
-
 Pyrococcus furiosus Met + Pro
-
 ?
Met-Pro + H2O
-
 Pyrococcus furiosus ATCC 43587 Met + Pro
-
 ?
Met-Pro + H2O
-
 Pyrococcus furiosus Vc1 Met + Pro
-
 ?
Met-Pro + H2O
-
 Pyrococcus furiosus JCM 8422 Met + Pro
-
 ?
Met-Pro-Ala + H2O
-
 Pyrococcus furiosus Met + Pro-Ala
-
 ?
Met-Pro-Ala + H2O
-
 Pyrococcus furiosus ATCC 43587 Met + Pro-Ala
-
 ?
Met-Pro-Ala + H2O
-
 Pyrococcus furiosus Vc1 Met + Pro-Ala
-
 ?
Met-Pro-Ala + H2O
-
 Pyrococcus furiosus JCM 8422 Met + Pro-Ala
-
 ?

Synonyms

Synonyms Comment Organism
M24B peptidase
-
 Pyrococcus furiosus
PepQ
-
 Pyrococcus furiosus
Pf-peptidase
-
 Pyrococcus furiosus
prolidase
-
 Pyrococcus furiosus
X-Pro dipeptidase
-
 Pyrococcus furiosus
Xaa-Pro dipeptidase
-
 Pyrococcus furiosus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
97
-
 assay at Pyrococcus furiosus

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
27
-
 Met-Ala-Ala pH 7.0, 97°C, recombinant wild-type Pyrococcus furiosus
102
-
 Met-Pro pH 7.0, 97°C, recombinant wild-type Pyrococcus furiosus
192
-
 Met-Pro-Ala pH 7.0, 97°C, recombinant wild-type Pyrococcus furiosus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
 assay at Pyrococcus furiosus

kcat/KM [mM/s]

kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
30
-
 Met-Ala-Ala pH 7.0, 97°C, recombinant wild-type Pyrococcus furiosus
107
-
 Met-Pro-Ala pH 7.0, 97°C, recombinant wild-type Pyrococcus furiosus
127
-
 Met-Pro pH 7.0, 97°C, recombinant wild-type Pyrococcus furiosus