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Literature summary for 3.4.13.22 extracted from

  • Jia, C.; Yang, K.; Liu, C.; Feng, L.; Xiao, J.; Zhou, L.; Zhang, Y.
    Synthesis, characterization and activity of new phosphonate dipeptides as potential inhibitors of VanX (2012), Bioorg. Med. Chem. Lett., 22, 482-484.
    View publication on PubMed
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Inhibitors

Inhibitors Comment Organism Structure
([(1-aminoethyl)(hydroxy)phosphoryl]oxy)acetic acid phosphonate dipeptide analogs of D-Ala-D-Ala Enterococcus faecium
2-([(1-aminoethyl) (hydroxy) phosphoryl]oxy)propanoic acid phosphonate dipeptide analogs of D-Ala-D-Ala Enterococcus faecium

Organism

Organism UniProt Comment Textmining
Enterococcus faecium
-
-
-

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.48
-
 pH 8.0, 37°C Enterococcus faecium ([(1-aminoethyl)(hydroxy)phosphoryl]oxy)acetic acid
0.76
-
 pH 8.0, 37°C Enterococcus faecium 2-([(1-aminoethyl) (hydroxy) phosphoryl]oxy)propanoic acid