Crystallization (Comment) | Organism |
---|---|
- |
Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Cilastatin | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | bound to | Homo sapiens | 16020 | - |
microvillus | the active site faces towards the microvillar membrane of a kidney tubule | Homo sapiens | 5902 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zinc | the active site in each of the (alpha/beta)8 barrel subunits of the homodimer molecule is composed of binuclear zinc ions bridged by the Glu125 side-chain located at the bottom of the barrel | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | the enzyme is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | - |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | tubule | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics | Homo sapiens | ? | - |
? |