Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.11.9 extracted from

  • Molinaro, G.; Carmona, A.K.; Juliano, M.A.; Juliano, L.; Malitskaya, E.; Yessine, M.A.; Chagnon, M.; Lepage, Y.; Simmons, W.H.; Boileau, G.; Adam, A.
    Human recombinant membrane-bound aminopeptidase P: production of a soluble form and characterization using novel, internally quenched fluorescent substrates (2005), Biochem. J., 385, 389-397.
    View publication on PubMed
Search for more literature for 3.4.11.9

Inhibitors

Inhibitors Comment Organism Structure
1,10-phenanthroline 50% inhibition at 0.01 mM Homo sapiens
apstatin 50% inhibition at 0.0023 mM Homo sapiens
additional information not inhibitory: bestatin, phosphoamidon Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.018
-
 K(Dnp)PPGFSPK(Abz)NH2
-
 Homo sapiens
0.019
-
 K(Dnp)PPK(Abz)NH2
-
 Homo sapiens
0.02
-
 K(Dnp)PPGK(Abz)NH2
-
 Homo sapiens
0.056
-
 des-Arg9-bradykinin pH 7.4, 37°C Homo sapiens
0.075
-
 bradykinin pH 7.4, 37°C Homo sapiens
0.837
-
 L-Arg-L-Pro-L-Pro pH 7.4, 37°C Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Homo sapiens 16020
-
soluble mutant form with translational stop codon at position 658 Homo sapiens
-
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein secreted enzyme mutant with translational stop codon at position 658, N-glycosylated Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
bradykinin + H2O
-
 Homo sapiens Arg + des-Arg-bradykinin
-
 ?
des-Arg9-bradykinin + H2O
-
 Homo sapiens ?
-
 ?
K(Dnp)PPGFSPK(Abz)NH2 + H2O
-
 Homo sapiens ?
-
 ?
K(Dnp)PPGK(Abz)NH2 + H2O
-
 Homo sapiens ?
-
 ?
K(Dnp)PPK(Abz)NH2 + H2O
-
 Homo sapiens ?
-
 ?
L-Arg-L-Pro-L-Pro + H2O
-
 Homo sapiens L-Arg + L-Pro-L-Pro
-
 ?